The Parish Church of St Margaret is a Church of England parish church situated on St Margaret's Road, off Bury Old Road (A665) in Prestwich, Greater Manchester, England. The Grade II listed church, in the Diocese of Manchester, was designed in the Decorated style by the Manchester architects Travis and Mangnall in 1849 as a chapel-of-ease to the ancient Prestwich Parish Church of St Mary the Virgin. Opened in 1851, it was extended in 1863, 1871, 1884, 1888 and 1899, and is notable for its fine Arts and Crafts wood carvings by Arthur Simpson of Kendal and late twentieth-century fittings. The church's daughter church of St George, Simister, is in the same parish.